With the amount of data currently being generated, we are in a unique position to find diagnoses and treatments for a multitude of diseases. However, the progress of lab technologies in generating data ...
Stereochemical configuration is determined by the relationship of atoms in three-dimensional space, yet remains most commonly represented in two-dimensional media such as printed publications or computer screens. Recommendations are provided for the display of three-dimensional stereochemical information in two-dimensional diagrams in ways that avoid ambiguity and are likely to be understood correctly by all viewers. Examples are provided for all types of stereochemical configuration, with explanation of which styles are preferred and which should be avoided.
Principal recommendations include:
Know your audience: Diagrams that have a wide audience should be drawn as simply as possible.
Avoid ambiguous drawing styles.
Avoid the use of perspective diagrams and class-specific drawing styles
(Fischer projections, Haworth projections, etc.) when structures are to be interpreted
Use solid wedges to indicate bonds that project above the plane of the paper
and hashed wedges to indicate bonds that project below the plane of the
paper; in both cases, the bonds must be oriented with the narrow end at the
Avoid connecting stereogenic centers with a stereobond.
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