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    • A Nobel for Autophagy: High Content Screening is Essential to Understanding this Cell Recycling Mechanism

    • Although the concept of autophagy — the process for degrading and recycling cellular components — has been around since the 1960s, a deeper understanding of this cellular mechanism wasn’t realized until Yoshinori Ohsumi  began experimenting with yeast to identify the genes involved in autophagy, beginning in the 1990s. His discoveries won him the 2016 Nobel Prize in Physiology or Medicine, announced this past October.Ohsumi’s work “led to a new paradigm in our understanding of how the cell recycles its content,” the Nobel Assembly at Karolinska Institutet, which ...
    • Technology Tackles Tough Biologics Challenges

    • If you watch TV and know anything about pharmaceutical drugs, you know biologics have arrived. Sufferers of rheumatoid arthritis (among other conditions) see advertisements for Humira, Remicade, and Enbrel – all top-selling biologics. Rituxan, Avastin, and Herceptin are best sellers in cancer treatment. Diabetes, Alzheimers, HIV/AIDS, and other major diseases have biologic treatments now. In fact, eight of the Top 10 best-selling drugs in 2015 were biologics.  Estimates for the global biologics market size vary, but it can be expected to grow nearly 11 percent ...
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